Bidentate P, N-P Ligand for nickel-catalyzed cross-coupling of aryl or benzyl chlorides with ArMgX.

A cross-coupling reaction of a variety of aryl, heteroaryl, and benzyl chlorides with ArMgX is catalyzed by 2 mol % of a nickel-phosphine complex prepared in situ from an equimolar amount of Ni(CH(3)CN)(2)Cl(2) and ligand (L2) to yield products in excellent yield in THF at room temperature. This new bidentate ligand (L2) is stable in air and forms a stable complex upon reaction with Ni(CH(3)CN)(2)Cl(2). Structures of the ligand and the complex were confirmed by single-crystal X-ray diffraction.

date completed: 2011-02-15
issue: 23
pmid: 21058667
article identifier: ['10.1021/jo1016458 [doi]']
volume: 75
status: PubMed-not-MEDLINE
source: J Org Chem. 2010 Dec 3;75(23):8283-6. doi: 10.1021/jo1016458. Epub 2010 Nov 8.
mesh date: 2010-11-10
date created: 2010-11-29
location identifier: 10.1021/jo1016458 [doi]
entrez date: 2010-11-10
language: ['eng']
affiliation: Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.
nlm unique id: 2985193R
origin: PubMed
date published: 2010 Dec 03
authors: ['Ghosh, Raju', 'Sarkar, Amitabha']
date last revision: 20101108
pages: 8283-6
publication status: ppublish
journal title abbreviation: J Org Chem
publication type: ['Journal Article']
owner: NLM
journal: The Journal of organic chemistry

Reference: .. [Ghosh+Sarkar:2010] Ghosh, Raju & Sarkar, Amitabha (2010). '**Bidentate P, N-P Ligand for nickel-catalyzed cross-coupling of aryl or benzyl chlorides with ArMgX.**' *The Journal of organic chemistry*. 75(23), pp. 8283-6.